The ASUS Transformer Prime is the first quad-core tablet, and users were a bit up in arms when it was discovered that the bootloader was locked.  ASUS responded with an official statement that a tool to unlock the bootloader was in development, and today their official Twitter account told everyone that it would be coming in February:

Of course, you'll be voiding your warranty and all that good stuff if you choose to use it, but for most folks looking to root and hack at their device that's not a big issue. 

With just a few days left in January, we should be seeing something soonish.  Hang tight, and enjoy a few games while you're waiting.  I hear the Prime does them really, really well.

Source: @ASUS.  Thanks, Lyon21!